Katsuhiko Mikoshiba Selected Research

2-aminoethyl diphenylborinate

1/2018	Blocking IP3 signal transduction pathways inhibits melatonin-induced Ca2+ signals and impairs P. falciparum development and proliferation in erythrocytes.
5/2015	Simultaneous administration of 2-aminoethyl diphenylborinate and chloroquine reverses chloroquine resistance in malaria parasites.

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Katsuhiko Mikoshiba Research Topics

Disease

12	Neoplasms (Cancer) 01/2022 - 09/2003
5	Malaria 01/2018 - 01/2012
5	Hypertrophy 01/2017 - 02/2009
5	Chagas Disease (American Trypanosomiasis) 12/2016 - 03/2013
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 10/2006
3	Infections 01/2020 - 05/2015
3	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2019 - 06/2017
3	Huntington Disease (Huntington's Disease) 01/2018 - 12/2011
3	Pancreatitis 02/2015 - 06/2009
2	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2019 - 01/2018
2	Ataxia (Dyssynergia) 11/2018 - 01/2015
2	Nervous System Heredodegenerative Disorders 01/2018 - 08/2012
2	Nervous System Diseases (Neurological Disorders) 01/2017 - 12/2009
2	Tetanus 05/2016 - 04/2012
2	Alzheimer Disease (Alzheimer's Disease) 11/2013 - 02/2005
2	Cardiomegaly (Heart Hypertrophy) 11/2012 - 09/2010
2	Systemic Scleroderma (Systemic Sclerosis) 09/2007 - 01/2007
2	Astrocytoma (Pilocytic Astrocytoma) 05/2004 - 02/2003
2	Stomach Neoplasms (Stomach Cancer) 10/2003 - 09/2003
2	Seizures (Absence Seizure) 12/2002 - 04/2002
2	Melanoma (Melanoma, Malignant) 04/2002 - 03/2002
1	Status Epilepticus (Complex Partial Status Epilepticus) 10/2021
1	Contact Dermatitis (Eczema, Contact) 01/2021
1	Pain (Aches) 11/2020
1	Hypersensitivity (Allergy) 11/2020
1	Chronic Pain 11/2020
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2020
1	Hypoxia (Hypoxemia) 04/2019
1	Pulmonary Arterial Hypertension 04/2019
1	Spinocerebellar Ataxia 29 11/2018
1	Carcinogenesis 11/2018
1	Pathologic Processes 01/2018
1	Neuroblastoma 01/2018
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2018
1	Alexander Disease (Alexander's Disease) 01/2018
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 07/2017
1	Carcinoma (Carcinomatosis) 06/2017
1	Brain Diseases (Brain Disorder) 01/2017
1	Color Vision Defects (Color Blindness) 01/2017
1	Epilepsy (Aura) 01/2017
1	Gliosis 01/2017
1	Ischemia 01/2017
1	Parkinson Disease (Parkinson's Disease) 01/2017
1	Communicable Diseases (Infectious Diseases) 06/2016
1	Infarction (Infarctions) 02/2016
1	Inflammation (Inflammations) 01/2016
1	Hypotension (Low Blood Pressure) 06/2015

Drug/Important Bio-Agent (IBA)

14	Inositol 1,4,5-Trisphosphate Receptors (Inositol Triphosphate Receptor)IBA 04/2019 - 09/2003
13	Proteins (Proteins, Gene)FDA Link 01/2020 - 04/2002
6	Pharmaceutical PreparationsIBA 10/2021 - 07/2004
5	CalciumIBA 01/2018 - 04/2011
5	Messenger RNA (mRNA)IBA 06/2016 - 12/2002
4	CalcineurinIBA 07/2012 - 02/2009
3	polyglutamineIBA 01/2018 - 12/2011
2	Protein Isoforms (Isoforms)IBA 01/2022 - 01/2015
2	AntibodiesIBA 01/2020 - 01/2007
2	Peptides (Polypeptides)IBA 01/2020 - 01/2018
2	Inositol 1,4,5-TrisphosphateIBA 01/2019 - 01/2018
2	MelatoninIBA 01/2018 - 03/2014
2	2-aminoethyl diphenylborinateIBA 01/2018 - 05/2015
2	Inositol (Myoinositol)IBA 01/2017 - 10/2003
2	2,3,6-trichloroindophenolIBA 12/2016 - 06/2016
2	Angiotensin IIIBA 06/2015 - 09/2010
2	Isoproterenol (Isoprenaline)FDA LinkGeneric 09/2010 - 02/2009
2	Peptide Hydrolases (Proteases)FDA Link 06/2009 - 09/2003
2	Syntaxin 1IBA 05/2004 - 02/2003
2	Complementary DNA (cDNA)IBA 10/2003 - 09/2003
2	Pentylenetetrazole (Metrazol)IBA 12/2002 - 04/2002
1	Oxidoreductases (Dehydrogenase)IBA 01/2022
1	Tricarboxylic AcidsIBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2021
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 11/2020
1	Capsaicin (Zostrix)FDA Link 11/2020
1	Analgesics (Analgesic Drugs)IBA 11/2020
1	Duloxetine Hydrochloride (Cymbalta)FDA Link 11/2020
1	ThapsigarginIBA 04/2019
1	Carbonic Anhydrases (Carbonic Anhydrase)IBA 11/2018
1	CarcinogensIBA 11/2018
1	Glial Fibrillary Acidic ProteinIBA 01/2018
1	Apoptosis Regulatory ProteinsIBA 01/2018
1	Stromal Interaction Molecule 2IBA 01/2018
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2018
1	TensinsIBA 01/2018
1	Promyelocytic Leukemia ProteinIBA 01/2018
1	DPB162-AEIBA 06/2017
1	Carisoprodol (Soma)FDA LinkGeneric 01/2017
1	Dopamine (Intropin)FDA LinkGeneric 01/2017
1	LithiumIBA 01/2017
1	Cyclic NucleotidesIBA 01/2017
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2017
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2017
1	OpsinsIBA 01/2017
1	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 05/2016
1	Interleukin-6 (Interleukin 6)IBA 01/2016
1	LipopolysaccharidesIBA 01/2016

Therapy/Procedure

4	Therapeutics 11/2018 - 05/2007
1	Precision Medicine 11/2018
1	Transplantation 02/2016
1	Ligation 02/2016